Advanced Physics for Brachytherapy 2018

Inverse Planning – using HIPO

~

M

kASDP

N

N

i j

2

i jkl

d       ) , , ( w t r f

feasible

=

(x)

d Sxb

1 =  = m

fw f m m =

Minimise

lk K lk k ,

=

=

k

1

l

1

Prostate = 25 cm³

0.0 0.1 0.2 0.3 0.4 0.5 0.6 0.7 0.8 0.9 1.0 1.1 1.2 Normalised Objective Value w=10 w=20 w=5 PTV

Aggregated PTV high

PTV low Urethra Rectum

w=10

8

10

12

14

16

18

Number of Catheters

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