Advanced TP

Relative risk

Lung cancer n=631,021 1.39 (1.28-1.51) 1.59 (1.39-1.81) 1.66 (1.36-2.01)

Esophageal cancer n=413,650

Thyroid cancer n=322,461 0.96 (0.59-1.57) 1.53 (0.69-3.39) 2.21 (0.64-7.61)

1.53 (1.01-2.31) 1.56 (1.03-2.38) 2.17 (1.11-4.25)

≥ 5 years ≥ 10 years ≥ 15 years

Risk of lung and esophageal cancer: • increased after breast radiotherapy • increased by time following breast cancer diagnosis • Increased with delivered Gy

However, no information about age, smoking, chemotherapy, irradiated volumes older radiotherapy techniques