Advanced TP

Reliability of radiobiological evaluation • Possible solutions: 1. “Large database” modeling 2. Use of automatic computer bots 3. Multiparametric modeling  Inferential statistics  Bayesian approach  Use of support-vector-machines  Other… 4. Extension of data-mining in multi-centric perspective 5. Definition of multi-centric “ontology” for data classification and collection minimizing errors JO Deasy et al. Improving normal tissue complication probability models: the need to adopt a “data-pooling” culture. Int J Radiat Onc Biol Phys. 76, (3), S151–S154, 2010

V Valentini, N Dinapoli, A Damiani. The future of predictive models in radiation oncology: from extensive data mining to reliable modeling of the results. Future Oncol. (2013) 9(3), 311–313