Advanced TP

Multivariate NTCP model: use of logistic regression for fitting different covariates (in addition to dose): Parameters for clinical outcome: Salivary glands

1 − +

ˆ

NTCP

=

X

nn + + + + =  22 x x x β

β

β 0

β

β

X e β ˆ

11

1

NTCP

X β ˆ

Beetz I et al. Development of NTCP models for head and neck cancer patients treated with three-dimensional conformal radiotherapy for xerostomia and sticky saliva: The role of dosimetric and clinical factors. Radiother. Oncol. Volume 105, Issue 1, Pages 86–93.