Advanced TP

Parameters for clinical outcome: Salivary glands

Multivariate NTCP model: Selection of covariates:

Final model:

1 − +

NTCP

=

X e β ˆ

1

= X β ˆ -5.27 + 0.066*mean dose parotid glands + + 0.05*age + 0.916*baseline xerostomia score

Beetz I et al. Development of NTCP models for head and neck cancer patients treated with three-dimensional conformal radiotherapy for xerostomia and sticky saliva: The role of dosimetric and clinical factors. Radiother. Oncol. Volume 105, Issue 1, Pages 86–93. Baseline xerostomia score is a simple clinical evaluation before the treatment (dummy covariate): 0 : no xerostomia 1 : a bit of xerostomia