Advanced TP

Parameters for clinical outcome: Rectum Multivariate modeling for detecting rectal toxicity (G3 late rectal bleeding)

n   

n :

TD 50

: 82.5 Gy

0.046

i    = ∑

1

1

EUD

n Dv

⋅

;

NTCP

=

TD 50

: 93.1 Gy

Logistic regression:

i

i

k

50 EUD TD

  +

  

k :

TD 50

: 91.7 Gy

10.4

1

T Rancati et al. Inclusion of clinical risk factors into NTCP modeling of late rectal toxicity after high dose radiotherapy for prostate cancer. Radiother Oncol 100 (2011) 124–130.