Advanced TP

Parameters for clinical outcome: Urinary bladder

Whole bladder irradiation

10 15 20 25 30 35 40 45

RTOG G3 : gross hematuria/no clots

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Average dose EQD2 dose ( α/β = 6 Gy)

Incidence of > G3 late bladder toxicity (%) 0 5

30

40

50

60

70

Viswanathan AN et al. Radiation Dose-Volume effects of the urinary bladder. Int. J. Radiation Oncology Biol. Phys., Vol. 76, No. 3, Supplement, pp. S116–S122, 2010. Dose (Gy)