Advanced TP

Physical optimisations Limitations

 Quadratic dose difference may not reflect clinical objective  Properly ranking plans based on dose-volume objectives may fail

Objective: 50% of volume is to receive <50 G y

Score: Plan 1: 10 /100 × ( 100 – 50 ) 2 = 250 Plan 2: 50 /100 × ( 60 – 50 ) 2 = 50

Result: Plan 1 is rejected!

Courtesy of Aswin Hoffmann