BCRB 2018

19/09/2018

Scoring of side-effects: frequency

• Two aspects must be considered for documentation • Frequency • Early reactions can undergo considerable changes in clinical manifestation in short periods • Scoring at weekly basis: during and for some weeks after RT

• Late reactions develop slowly and are usually irreversible • Scoring at intervals of several months after the end of RT (dynamics) • At later time points at annual intervals

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Scoring of side-effects: frequency

• Progressive nature of late reactions

Breast Ca, post-op RT

Long latent times Large inter-patient variation

Turesson 1990

48