BCRB 2018

Dose fractionation: Time interval

mouse tongue mucosa,

22

20

early response

18

16

a / b =11.6 Gy T 1/2 =46 min

14

12

10

ED50 for fractionated irradiation [Gy] 0 60 120 180 240 300 360 420 480 540 8

Time between fractions [min]

Dörr et al., RTO 27, 1993, 36-45

ESTRO BCR Course / NT radiosensitivity and fractionation – W. Dörr