BCRB 2018

Conclusions

• Benefit of hyper- and accelerated fractionation for loco- regional control probability

• Slight increase in acute toxicity but no change in late toxicity

• Moderately hypofractionation for tumors with low a/b

• Extreme hypofractionation for well selected indications, e.g. small peripheral lung tumors (dose distribution effect only!)

ESTRO