BCRB 2018

Low-LET tracks in cell nucleus, e.g. from X-rays

High-LET tracks in cell nucleus, e.g. alpha particles

He 2+ Microdosimetry

A dose of 1 Gy corresponds to approx. 4 tracks

A dose of 1 Gy corresponds to approx. 1000 tracks

∼ 1 µ m

LET : L inear E nergy T ransfer. A measure of average ionization density. LET ∝ charge 2 velocity 2

Michael Joiner

Basic Clinical Radiobiology 2018

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