BCRB 2018
HIF and cancer
w Loss of VHL causes overexpression of HIF and renal cell carcinoma w HIF is overexpressed in many cancers • Mimics hypoxia biology in normoxia
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HIF and cancer
w Loss of VHL causes overexpression of HIF and renal cell carcinoma w HIF is overexpressed in many cancers • Mimics hypoxia biology in normoxia
Made with FlippingBook - Online catalogs