BCRB 2018

Treatment of advanced squamous-cell carcinoma of the head and neck with alternating chemotherapy and radiotherapy. M. Merlano et al, NEJM, 327:1115-1121, 1992.

Effect on tumor control

2

Local relapse

?

1

Early

Late

2

Effect on normal tissue toxicity

Enhancement factor

RT: 70 Gy, 7 weeks RT+CH: 3 x 20 Gy, 9 weeks;

ESTRO 2018

cddp (20mg/m 2 /d, d1-5)-5Fu (200 mg/m 2 /d, d1-5) x4