BCRB 2018

Changes in normal tissue tolerance with time

long-term restoration

recovery kinetics

repopulation

160 140 120 100

Long-term recovery from radiation injury in some tissues (not all!)

spinal cord

oral mucosa 80 60 40 20 0 0.00001 0.0001 0.001 0.01 0.1

Isoeffective dose (Gy)

1

10

100

Time interval (days)