Basic Clinical Radiobiology 2017

a) Heterogeneity in hypoxia (%) amongst patients

20

Normal tissue

15

10

5

Relative frequency (%)

0

Nordsmark et al. Acta Oncol 1994

0

20

40

60

80

Oxygen partial pressure (mmHg)

100

80

20

Tumour

60

15

40

10

20

Dead (n=42) Alive (n=24)

5

Relative frequency patients (%) 0

Relative frequency (%) 0 20 0

Fraction pO 2 < 2.5 mmHg (%) 0 10 20 30 40 50 60 70 80 90 100

40

60

80

Oxygen partial pressure (mmHg)