Basic Clinical Radiobiology 2017

Rectum

• Pre-op retreatment (hyperfractionation + chemotherapy) for rectal cancer • Initial dose ≤55Gy; med interval 27 months • Re-irradiation dose 30Gy + boost of 10.8Gy with 2x1.2Gy per day

Valentini Int J Radiat Oncol Biol Phys 2006

• Low acute toxicity and acceptable incidence of late complications