Basic Clinical Radiobiology 2017

Image-Guided Radiation Therapy in HNSCC Impact of imaging modality on CTV/PTV delineation

CT-scan FDG-PET Larynx/hypopharynx (n=9) ANOVA: p<0.05

Oropharynx (n=10)

200

100 150 200 250

CT-scan FDG-PET

150

ANOVA: p<0.01

100

50

0 50

Average (± sem) volume (cc)

0

Average (± sem) volume (cc)

GTV

CTV

PTV

GTV

CTV

PTV

ESTRO 2017

Geets et al , 2003

Impact of imaging modality on dose distribution Image-Guided Radiation Therapy in HNSCC CT-based target volume FDG PET-based target volume

ESTRO 2017