Basic Clinical Radiobiology 2017

Organoid radiation response assessment

Expansion

A ’

A

Organoids

Tumor & Normal Tissue

7 days

7 days

p 0

P2 ….Px

p 1

Cell suspension

biopsies

Expanded Organoids

Remaining Organoids forming unit frequency

Normal tissue organoid vs tumor organoid, therapeutic ratio?

Response to treatment?