Basic Clinical Radiobiology 2017

Late radiation effects: Summary

induction

progression

manifestation

parenchyma endothelium fibroblasts

loss of function

parenchymal damage

?

immune system (macrophages)

regene- ration

innervation

healing

latent time: inverse dose dependence

ESTRO BCR Course / Pathogenesis of NT effects – W. Dörr