Basic Clinical Radiobiology 2017

9/16/17

The “x” Rs of Radiotherapy • Radiosensitivity • Repair • Repopulation • Redistribution • Reoxygenation • iRradiated volume • Restoration (long term recovery) • Re-iRRadiation • another “R” still to be invented…

ESTRO 2017

Fractionation sensitivity

“Typical” dose per fraction • 1.8-2 Gy for standard fractionation • 1.1-1.3 Gy for hyper- fractionation

ESTRO 2017

Withers et al, 1983

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