Basic Clinical Radiobiology 2017

Repopulation: Mechanisms

450

mouse tongue mucosa

Observation 3: Compensation of normal cell loss

control

100

400

90

350

80

300

70

60

250

50

0 Gy/F 4 Gy/F 3 Gy/F

200

40

0 Cells / mm epithelial length 150

Relative cell number [% of control]

30

Overall treatment time [days] 5 10 15

Dörr et al., Int. J. Radiat. Biol. 66, 1994, 157-167

ESTRO BCR Course / NT overall treatment time – W. Dörr