Basic Treatment Planning

3DCRT vs. IMRT

• Retrospective study: MD Anderson  1996-2006  N= 496 NSCLC pts

 CT/3DCRT: 318 pts, Fup mean Time: 2.1 y  4DCT/IMRT: 91 pts, Fup mean time: 1.3 y  Median dose of 63 Gy.  HR OS > 1 in favour of 4DCT/IMRT (trend for LRC and DM)  Significantly lower toxicity with IMRT/4DCT  V20 was significantly higher in the 3DCRT group and was a significant factor in determining toxicity.  Freedom from DM was nearly identical in both groups.