Brachytherapy for Prostate Cancer 2017

Risk groups – Individual tumor characteristics:

Biopsies: at random - systematic Chance of hitting tumor per biopsy=15-20%

Gleason score: poorly reproducible Biopsy agreement with prostatectomy: (n=1670)

– Gleason 5-6 undergrading: 35% – Gleason 8-10 overgrading: 35%

PSA – Suspected linear relation with amount of tumor cells – Irreliable due to leakage, often false positive

Conclusion: Literature contains probably higher Gleason scores too