Brain 17 Vienna

WBRT +/- radiosurgery for brain metastases

100

80 20 Local progression free survival (%) 60 40

WBRT + SRS WBRT

WBRT alone

WBRT alone

local control

100

survival

80

60

40 Survival (%)

WBRT + SRS

20

WBRT alone

0

WBRT whole brain RT SRS stereotactic radiosurgery

0 RTOG 9508 Andrews et al 2004, Lancet; 363: 1665–72

6

12

18

24

Time (months)