Brain 17 Vienna

High Grade gliomas An Evidence Based Approach

• 33 publications • Extent of resection

improves TTP and OS  After gross total resection

 WHO grade III OS 64.9-75.2 m  WHO grade IV OS 11.3-18.5 m

Recurrent GBM benefits from gross total resection (selection bias)  19m total vs 15. for subtotal

Bloch O, Han SJ, Cha S, Sun MZ, Aghi MK, McDermott MW, Berger MS, Parsa AT (2012) Impact of extent of resection for recurrent glioblastoma on overall survival: clinical article. J Neurosurg 117:1032–1038