Brain 17 Vienna
Conclusions
Improvement of radiotherapy safety, with promising efficacy in patients with brain metastases Well defined dose constraints (QUANTEC, ESTRO, RTOG) New knowledge concerning the role of Neural Stem Cells permitted to identify brain regions involved in plasticity and repair processes (Hippocampus e.g.) Randomized controlled trials have demonstrated significant activity of Memantine and Donepezil for neurocognitive impairment prevention, in patients treated with cranial radiotherapy for primary and metastatic brain tumors Even with new treatments (BEV e.g.) radiation necrosis remains a challenge; better treatment for that is prevention
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