Brain 17 Vienna

Clinical case

History of present illness: 40 year old woman

2 generalized epileptic seizures in july 2000

Past Medical History: Several head traumas Hypothyroidism Migraine Initial CT-SCAN: Ipodense lesion in the left frontal lobe (2 cm) w/o contrast enhancement: attributed to a scar  initiate of carbamazepine Persistence of epileptic seizure: Minimal increase of MRI abnormality without contrast enhancement, with features of low grade glioma Therapy Biopsy at that time consistent with Anaplastic astrocytoma WHO III, no Molecular Biology  GTR + RT 66Gy/2Gy daily fractions (2000) (for MRC trial)