Brain Tumours

WBRT +/- radiosurgery for brain metastases

100 80 60 40 20 Local progression free survival (%)

WBRT + SRS WBRT

WBRT alone

WBRT alone

local control

100 80 60 40 20 0 Survival (%)

survival

WBRT + SRS

WBRT alone

WBRT whole brain RT SRS stereotactic radiosurgery

0 RTOG 9508 Andrews et al 2004, Lancet; 363: 1665–72

6

12

18

24

Time (months)