Brain Tumours

Conclusions: anaplastic gliomas

1p/19q co-deleted tumors:

• The combination of RT and PCV may be regarded as standard of care for newly diagnosed anaplastic oligodendroglial tumors with 1p/19q co- deletion

• RT -> PCV and PCV -> RT are both feasible options • Temozolomide instead of PCV? => no final answer so far

Non-1p/19q co-deleted tumors: • RT as current standard for newly diagnosed cases • Role of temozolomide to be defined in CATNON trial