Brain Tumours

Outcome (RT alone, chx – RT, chx. alone) Radiotherapy in pure germinoma

Author Bamberg 1999

Pat.

RFS (5 years)

Therapy

11 49 44 45

RT CSA 36 Gy+Tu 14 Gy RT CSA 30 Gy+Tu 15 Gy

100% 88.8%

Bouffet, 1999

Chx. + RT tumour

98% (3 years)

Balmaceda, 1996

Chx. alone

50%

12 RT CSA/tumour 11 RT whole brain/tumour 24 RT ventricular system Chx. / RT tumour : 24 Gy 23 RT CSA/tumour 10 RT whole brain / tumour 8 RT tumour 30 RT CSA/tumour 10 RT whole brain/tumour Chx. / RT tumour region

10 y. 94% 94% 0%

Haddock, 1997

48

Kitamura, 1999

13 41

100%

10 y. 90% 76% 22%

Aoyama, 1998

Hardenbergh, 1997

40

100% 100%

Cefalo, 1995 Kellie, 2004 Da Silva 2010 Kortmann, 2001

7

5 relapses (ventricles) 47% 6 y : 45.6% / OS 75.3%

11 25

Chx. alone

155

102 RT CSA 53 other treatments

99.5% (CNS) 49% (CNS )

8 y. EFS 89%, OS 91%

Shikama, 2005

180

114 RT whole brain / Boost