Brain Tumours

Lower-grade gliomas with an IDH mutation and 1p/19q codeletion were of the oligodendroglioma histologic class and were associated with favorable outcomes .

Handling Histo-molecular criteria

Tumors with wild-type IDH were molecularly and clinically distinct from subtypes with mutated IDH , with most showing a striking resemblance to primary glioblastoma on all analytic platforms

It may transpire that distinct therapeutic strategies are required for effective disease control in molecular subtypes of lower-grade glioma.