Brain Tumours

Radiotherapy in pure germinoma

Pattern of relapse after chx followed by RT With respect to target volume (M0) Local RT versus ventricular RT

Author

Pat. Dose/Gy

RFS n.a. 66%

OS

relapses 5 (71,5%)

Cefalo, 1995 Aoyama, 2002 Lafay-Cousin 2006 Bouffet, 1999 Matsutani, 2001 Nguyen, 2006

7

40 local 24 local

100% 93,8% 100%

28

6 (21%) 0 (0%) 4 (7%) 9 (12%) 4 (44%)

6

24-40 WV

100%

57 75

40 local 24 local

96,4%

98% n.a. 89%

n.a. n.a

9

30.6 local

Relapses (majority ventricular system) after local RT in all series 16% (6-71,5%)

Modified according to Aoyama et al., 2009