Brain Tumours

MTX-based therapy in elderly patients Prospectively collected study data

n

age

Treatment

CR

PR PFS OS

Omuro

23

68

55% 0%

8

35

MTX, Temozolomide

MTX, CCNU, PCZ, Prednisolone. MTX and AraC i.th.

Hoang- Xuan

42% 6 % 10.6 14.3

50

72

MTX, CCNU, Procarbazine

Illerhaus

30

70

44% 26% 5.9 15.4

MTX, CCNU, PCZ, Rituximab MTX, ifosfamide, +/- WBRT

Fritsch

28

76

64% 18% 16 17.5

Roth

126

73

30% 14%

4.0

12.5

62% 45%

26% 20%

9.5 6.1

31 14

MTX, PCZ, VCR, AraC MTX, TMZ

Omuro

95

73