Brain Tumours

Einschlusskriterien Key inclusion criteria

Author Division Olaf Witt SIOP LGG 201X

PAge70 1/25/2016 | a

• age: 0 -20.99 years • histologically verified LGG • collection of fresh frozen tumor tissue for biomarker determination mandatory . Exception: single cases of stereotactic biopsy in which larger biopsy would impose unacceptable risk to patient • Indication to start chemotherapy: progressive disease on MRI, neurological function, visual function, •all infants < 1 year

no default first line radiation therapy