CPB Budapest 2017

HDR- ICBT: late complications

Clinical Data

HDR vs LDR

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Review literature * (Fu and Phillips 1990) Meta-analysis 17 068 pts (Orton 1991)

G2-4 12.0% 18.0%

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G3-4 2.2% 5.3% p<0.001

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Randomised Phase III

(Patel 1994)

G1-4 6.4% 19.9% p<0.001 G3-4 0.4% 2.4% p> 0.05

* majority Fx 7.8 Gy to point A