CPB Ljubljana 2018 course book
Effect of chemotherapy
Cochrane metaanalysis
▪ 13 trials, 3128 patients ▪ Individual data ▪ OS : +6% at 5 y, HR = 0.81 ▪ Benefit for LC and meta ▪ Platinum or non platinum ▪ Mainly for stage I-II ▪ No effect of age, nodal status
Cisplatin weekly 40 mg/m2
Chemoradiotherapy for Cervical Cancer Meta- Analysis Collaboration, J Clin Oncol 2010
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