CPB Ljubljana 2018 course book

• Most available outcome data come from the LDR Ir-192-wire era and should be used as a reference. • HDR is used 2 fractions per day with a minimum of 6 h interval to allow complete repair of sublethal damage. RECOMMENDATIONS FOR DOSE

Mono Gy

Boost Gy

Surgery + BT

PDR 0.4Gy 24

70

30 50-64

Strnad / Peiffert

pulses/day

PDR 0.8Gy 12 pulses/d 60

30-35 50-60 Base of tongue / lip Johansson

HDR 2.5 Gy 2 fx/day

34-36 10-20 30-36 DNR >0.5

Strege / Kovacs

HDR 3 Gy 2 fx/day

-

18-21 51-54 Tongue / oropharynx Takacsi-Nagy / Petera

HDR 4 Gy 2 fx/day

44 48

16-24 16-20

32-40 40-44

Tongue/ oropharynx Martinez-Monge / Guinot

HDR 5 Gy 2 fx/day

45

-

40.5(4.5) Lip needles

Guinot

HDR 6 Gy 2 fx/day

48

18-24 -

Oropharynx

Nose / Inoue/ Yamazaki

60

Tongue single line