CPB Ljubljana 2018 course book

PDR in H&N carcinoma

1997-2009, 385 H&N cancer. PDR-iBT 0.4-0.7 Gy each hour, 24 h per day

Surgery + BT in 326 (84.7%) 246 (63.9%) iBT alone 135 (36.1%) EBRT + BT Median FU 63 months.

5- 15-year local control 85.8% 83.1% 80.2% DFS 81.3% 79.3% 76.3% Local control for N0-/N1: 92.3% N2 : 73.7% 10-

Soft tissue necrosis:

10.2%

2013

Bone necrosis:

4.9%

Strnad V. Interstitial pulsed-dose-rate brachytherapy for head and neck cancer-single-institution long-term results of 385 patients. Brachytherapy 2013; 12:521-527