CPB Ljubljana 2018 course book
PDR REIRRADIATION FOR RECURRENCE
• 104 patients recurrent H&N cancer with PDR BT. • median FU 60 m. • Salvage surgery in 53/104 (51%) (R1 or R2 resection in > 80%).
• Salvage BT alone: 81 (78%), dose 56.7 Gy • Salvage BT + EBRT: 23 (32%), dose 24 Gy • Concomitant chemotherapy 55.8% • A single session of interstitial hyperthermia in 31.7%
• RESULTS:
2y 5y 10 years 92.5 82.4 58.9%
• local tumor control
with simultaneous chemo:
76 % 39 %
without chemo
• Soft tissue necrosis: 17.3% • bone necrosis: 9.6% (only 3% required surgical treatment)
Strnad V. Reirradiation for recurrent head and neck cancer with salvage interstitial pulsed-dose-rate brachytherapy: Long-term results.Strahlenter Onkol 2015; 191:495-500
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