CPB Ljubljana 2018 course book

10 Gy vs 26 Gy LDR boost with positive margins

251 patients LDR boost

Severe fibrosis

3%

17.5%

n.s.

13%

10.8%

Poortmans PM et al. Impact of the boost dose of 10 Gy versus 26 Gy in patients with early stage breast cancer after a microscopically incomplete lumpectomy: 10-year results of the randomised EORTC boost trial. Radiother Oncol. 2009 Jan;90(1):80-5.