Cervix BT - 2016

Hyperthermia & Brachytherapy

“Dutch hyperthermia trial, 12 y FU”

Historical Paris

Stockholm Manchester Fletcher

RT+HT RT

RT+HT RT

Overall survival

Pelvic tumor control Years

Years

Toxicity: comparable Franckena M, et al. IJROBP 2008;70:1176-1182.

Limitations of IC Applicators Modern Stockholm Manchester & Fletcher Mould

From: Datta NR, et al. Cancer Treatment Reviews 2015

Lutgens L, et al. Cochrane Database Syst Rev CD006377

Overall Survival

Local recurrence

Complete remission

Datta NR, et al. Cancer Treatment Reviews 2015;41:742-753. Mallory M, et al. Critical Rev in Oncol / Hematol 2016;97:56-64. Warrel G, et al. Med Phys. 2015;42(6):3709. Chen X, et al. Int J Hyperthermia. 2010;(1):39-55.

Lutgens L, et al. Cochrane Database Syst Rev CD006377 Franckena M, et al. IJROBP 2008;70:1176-1182. Franckena M, et al. IJROBP 2009;73:242-50. Franckena M, et al. Eur J Cancer 2009;45:1969-1978.

Emerging

Technologies