Course book Advanced Treatment Planning 2018

Replanning H&N IMRT patients

• Causes of anatomy variations:

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Tumor shrinkage

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Weight loss (mucositis, reduced caloric intake)

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Radiation induced anatomical changes (parotid glands)

• Significant variations for dose to OAR (generally increased) • Variations of target coverage

Adaptive RT

Castadot, P., Lee, J. a., Geets, X. & Grégoire, V. Adaptive Radiotherapy of Head and Neck Cancer. Semin. Radiat. Oncol. 20, 84–93 (2010).