Course book Advanced Treatment Planning 2018

Equivalent Uniform Dose

➢ The EUD is base on the assumption that two dose distributions are equivalent if they produce the same radiobiological or clinical effect (end-point) ➢ D j : the dose in the volum bin ➢ v j : volum bin ➢ a : parameter that describes the serial/parallel structure of the organ

1

j     =  = 1

   

a

a j Dv

EUD

j

Niemierko A. A Concept of Equivalent Uniform Dose (EUD). Volume & Kinetics in Tumor Control & Normal Tissue Complications. 5 th International Conference on Dose, Time and Fractionation in Radiation Oncology. 1998