Course book Advanced Treatment Planning 2018

The Volume Effect in OAR

1

V

   

   

a

reference

VD

VD

(

)

=

(

)



irradiated

reference

V

irradiated

1. a value is function of the structure: Spinal cord (>20) Lung ( 1) 2. Within a structure a can be function of the effect: Rectal bleeding (Rectum)

Necrosis (Brain)

Proctitis (Rectum)

Dementia (Brain)

3. Within a structure a can be function of the anatomy

Marks LB, et al. Use of normal tissue complication probability models in the clinic. Int. J. Radiat. Oncol. Biol. Phys. 2010 (76-3): S10-S19.