Course book Advanced Treatment Planning 2018

Parameters for clinical outcome: Brainstem

Endpoint: Brainstem necrosis or neuropathy

70

60

55

40

35

20

Total Dose (Gy)

10

0

0

2

4

6

8

10

12

14

16

18

Dose per Fraction (Gy)

Mayo C et al. Radiation associated brainstem injury. Int. J. Radiation Oncology Biol. Phys., Vol. 76, No. 3, Supplement, pp. S36–S41, 2010.