Course book Advanced Treatment Planning 2018

Parameters for clinical outcome: Salivary glands

Mean percentage of reduction in stimulated salivery flow rate vs. mean parotid gland dose for different follow-up durations

100

80

Months of Follow-up 1 6 12

60

1 month

Eisbruch Macs Bream

40

time

Roesink 2001 Roesink 2004 Bussels Saarilahti

6 months

20

12 months

0 Reduction in Stimulated Salivary Flow Rate (%) -20 0 20

40 60 Mean Parotid Gland Dose (Gy)

Deasy JO et al. Radiation Dose-Volume effects on the salivary gland function. Int. J. Radiation Oncology Biol. Phys., Vol. 76, No. 3, Supplement, pp. S58–S63, 2010.