Course book Advanced Treatment Planning 2018

Parameters for clinical outcome: Salivary glands

Population-based dose vs. local function response (salivary function on rest) from imaging study

Dmean < 25 Gy Parotid gland function reduction of 25% < 20% 39 5

100

80

60

40

20

0 20 Parotid gland function (%) 0 40

60

Radiation dose (Gy)

Deasy JO et al. Radiation Dose-Volume effects on the salivary gland function. Int. J. Radiation Oncology Biol. Phys., Vol. 76, No. 3, Supplement, pp. S58–S63, 2010.