Dose 2016

Action limits - Proposed philosophy

Define the center of the true dose probability distribution as the lower and upper action limit , respectively.

Step 4:

Prescribed dose

Probability distribution for the true dose

Dose (Gy)

is set to a minimum acceptable cure rate

is set to a maximum acceptable complication rate

TL

TL

−∆

+∆

Clinical tolerance limits

From Jörgen Olofsson (Dose Modeling and dose verification ESTRO COURSE)