Dose 2016

Invariant and Variant Dose Distributions Cho et al MP 2002

• Invariant (main effect on DVH):

– Negligible dosimetric effect from contour or tissue inhomogeneity effects as function of displacement

• Variant (secondary effect):

– Due to tissue inhomogeneity and contour effects as well

• Conclude:

– Differences in relative volume and relative dose depending on displacement – Variant effects of contour changes, inhomogeneities and set up are negligible on EUD

Note: Worst case!

Utrecht 2016